Red vs. Blue: The Blood Gulch Chronicles, often abbreviated as RvB, is a machinima comic science fiction video series created by Rooster Teeth Productions and distributed primarily through the Internet and DVD. The series chronicles the story of two opposing teams of soldiers fighting a civil war in the middle of a desolate box canyon (Blood Gulch), in a parody of first-person shooter (FPS) games, military life, and science fiction films. Initially intended to be a short series of six to eight episodes, the project quickly and unexpectedly achieved significant popularity following its April 1, 2003, Internet premiere. Rooster Teeth therefore decided to extend the series, eventually totaling five seasons and 100 episodes.

Red vs. Blue emerged from Burnie Burns' voice-over-enhanced gameplay videos of Bungie Studios' FPS video game Halo: Combat Evolved. The series is primarily produced using the machinima technique of synchronizing video footage from a game to pre-recorded dialogue and other audio. Footage is mostly from the multiplayer modes of Halo: Combat Evolved and its sequel, Halo 2, on the Microsoft Xbox video game console.